Research
CAR-NK
The project is a collaboration study with Prof. Alex Mc Lellan from the Department of Microbiology and Immunology at Otago University, New Zealand. I have gotten a small grant from DIPI to start the project in the Department of Clinical Microbiology, Faculty of Medicine, Universitas Indonesia. My supervisor from UI is dr. Rina la Distia Nora, Sp.M(K)., PhD & Fithriyah, PhD. We will look for the potential role of CAR-NK in TB infections. (ongoing)
Immunology of HIV patients
The Collaborative Research Between Universitas Indonesia and Curtin University on Cytomegalovirus co-infection in HIV patients. We have discovered the role of several immune cells linked with clinical outcomes.
CD4 and CD8 T-cells
Natural killer cells
Gamma Delta T cells (ongoing)
Cytomegalovirus
The CMV research has been done in HIV patients starting ART, followed by 5 years in the JakCCANDO Study.
Currently working with Biomedical Science UI PhD student Isti Anindya to understand CMV's role in the cognitive development of Autism Spectrum Disorder (ASD) children (the principal investigator was Prof. Amin Subandrio). (ongoing)
We have been investigating CMV IL10 and human IL10R SNPs with Curtin/UWA Researcher Shelley Waters. The research also part of the Master Research of Yudha Fariska (master Student of Biomedical Science) (ongoing)
Molecular viability assay of Mycobacterium lepra
I am co-supervisor of Clara Imaniar (master Student of Biomedical Science). The main supervisor is Prof Yeva Rosana (Dept. Microbiology FMUI). Our main goal is to develop a molecular method to identify live M. lepra from clinical samples. (ongoing)
COINCIDE Project
I am participating in the COINCIDE Project. Working under Prof. Anis Karuniawati Project, I am collaborating with Soe You Naing - Utrecht University. The project involving microbiology specialist student dr.Lili. (ongoing)
Vaccine Development (2021-2023)
I am working with a Master's student in biomedical science at the Faculty of Medicine (Raisha Muhayya), Universitas Indonesia. Her work is to develop recombinant SARS-CoV-2 vaccine construction. The vaccine design used a bioinformatic approach to predict the optimal epitope for T-cell response. (end)
Infectious Diseases Molecular Diagnostics Development (2021-2022)
Work with a private company to validate qPCR kits (end)
journal reviewers
I have participated in a peer review in
Dovepress (Journal of Inflammation Research & Journal Infection and Drug Resistance)
Journal of Infection in Developing Countries (JIDC)
Acta Tropicana (Elsevier)
AIDS Research and Therapy (Springer Nature)
PUBLICATIONS (last update Sept 21, 2024)
Amanah, Amanah, Ibnu Agus Ariyanto, Budiman Bela, Risnandya Primanagara, and Pratiwi Sudarmono. 2024. “Evaluation of the Effect of mRNA and Inactivated SARS-CoV-2 Vaccines on the Levels of Cytokines IL-2, IFN-γ, and Anti-RBD Spike SARS-CoV-2 Antibodies in People Living with HIV (PLHIV).” Biomedicines 12 (9): 2115.
Amanah, Amanah, Budiman Bela, S. T. Widyaningtyas, Ibnu Agus Ariyanto, and P. Sudarmono. 2024. “A Review of the Relationship between CD4 T-Lymphocytes and Efficacy of COVID-19 Vaccines in People Living with HIV (PLWH).” THE 7TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, AND MEDICAL DEVICES: The 15th Asian Congress on Biotechnology in Conjunction with the 7th International Symposium on Biomedical Engineering (ACB-ISBE 2022). https://doi.org/10.1063/5.0200961.
Ariyanto, Ibnu A., Riwanti Estiasari, Lukman Edwar, Nandini Makwana, Silvia Lee, and Patricia Price. 2019. “Characterization of Natural Killer Cells in HIV Patients Beginning Therapy with a High Burden of Cytomegalovirus.” Immunological Investigations 48 (4): 345–54.
Ariyanto, Ibnu A., Riwanti Estiasari, Birry Karim, Ika Praseya Wijaya, Budiman Bela, Amin Soebandrio, Patricia Price, and Silvia Lee. 2022. “Which NK Cell Populations Mark the High Burden of CMV Present in All HIV Patients Beginning ART in Indonesia?” AIDS Research and Therapy 19 (1): 16.
Ariyanto, Ibnu A., Riwanti Estiasari, Silvia Lee, and Patricia Price. 2022. “Γδ T Cell Subpopulations Associate with Recovery of Memory Function in Indonesian HIV Patients Starting Antiretroviral Therapy.” AIDS Research and Human Retroviruses 38 (9): 764–70.
Ariyanto, Ibnu A., Riwanti Estiasari, Shelley Waters, Endah A. T. Wulandari, Sonia Fernandez, Silvia Lee, and Patricia Price. 2018. “Active and Persistent Cytomegalovirus Infections Affect T Cells in Young Adult HIV Patients Commencing Antiretroviral Therapy.” Viral Immunology 31 (6): 472–79.
Ariyanto, Ibnu A., Silvia Lee, Riwanti Estiasari, Jeanne Edmands, Budiman Bela, Amin Soebandrio, and Patricia Price. 2021. “Understanding the Effects of CMV on Γδ T-Cell Populations in HIV Patients Starting Antiretroviral Therapy.” Clinical Immunology 226 (May): 108696.
Dmello, Deane Maria, Ibnu Ariyanto, Riwanti Estiasari, Samuel Halstrom, Jessica Gaff, Silvia Lee, and Patricia Price. 2017. “Polymorphisms in IL10 May Alter CD4 T-Cell Counts in Indonesian HIV Patients Beginning Antiretroviral Therapy.” Human Immunology 78 (4): 387–90.
Edwar, Lukman, Ibnu Agus Ariyanto, Selita Agnes Tanudjaja, Ratna Sitompul, Silvia Lee, and Patricia Price. 2021. “Interleukin-1A May Illuminate Differential Effects of the Retinal Artery Caliber in HIV Patients.” Molecular and Cellular Biomedical Sciences 5 (2): 88.
Edwar, Lukman, Phuongnhi Ha, Ibnu A. Ariyanto, Riwanti Estiasari, Ratna Sitompul, Silvia Lee, and Patricia Price. 2021. “A TNF Block Genotype May Influence CMV Retinitis in HIV Patients without Affecting Systemic Viral Replication.” Current HIV Research 19 (1): 96–99.
Edwar, Lukman, Birry Karim, Ika Prasetya Wijaya, Ibnu Ariyanto, Selita Agnes Tanudjaja, Riwanti Estiasari, Ratna Sitompul, and Patricia Price. 2019. “Factors Affecting the Health of Retinal Vessels in Human Immunodeficiency Virus Patients Beginning Anti-Retroviral Therapy.” AIDS Research and Human Retroviruses 35 (6): 529–35.
Gaff, J., F. Octaviana, P. Pillay, Huguette Gaelle Ngassa Mbenda, Ibnu A. Ariyanto, June Anne Gan, C. Cherry, P. Kamerman, S. Laws, and P. Price. 2020. “TNF-Block Genotypes Influence Susceptibility to HIV-Associated Sensory Neuropathy in Indonesians and South Africans.” International Journal of Molecular Sciences 21 (2): 380.
Gaff, Jessica, Fitri Octaviana, Ibnu Ariyanto, Catherine Cherry, Simon M. Laws, and Patricia Price. 2019. “Polymorphisms in CAMKK2 Associate with Susceptibility to Sensory Neuropathy in HIV Patients Treated without Stavudine.” Journal of Neurovirology 25 (6): 814–24.
Karim, Birry, Ika Praseya Wijaya, Rizky Rahmaniyah, Ibnu Ariyanto, Shelley Waters, Riwanti Estiasari, and Patricia Price. 2017. “Factors Affecting Affect Cardiovascular Health in Indonesian HIV Patients Beginning ART.” AIDS Research and Therapy 14 (1): 52.
Mountford, Jenjira, Fitri Octaviana, Riwanti Estiasari, Denise Dewanto Setiawan, Ibnu Ariyanto, Silvia Lee, Jessica Gaff, et al. 2018. “Ex-Vivo Expression of Chemokine Receptors on Cells Surrounding Cutaneous Nerves in Patients with HIV-Associated Sensory Neuropathy.” AIDS (London, England) 32 (4): 431–41.
Muhayya, Syarifah Raisha, Ibnu Agus Ariyanto, Silvia Widianingtyas, Tanaya Subiantistha, and Budiman Bela. 2024. “SARS-CoV-2 Multi-Epitope Subunit Vaccine Proof-of-Concept Derived from the Insilico Study with Protein Expression in Escherichia Coli BL21.” Pharmaceutical Journal of Indonesia 9 (2). https://doi.org/10.21776/ub.pji.2024.009.02.1.
Noviantari, Ariyani, R. Rinendyaputri, and Ibnu A. Ariyanto. 2020. “Differentiation Ability of Rat‐mesenchymal Stem Cells from Bone Marrow and Adipose Tissue to Neurons and Glial Cells.” Indonesian Journal of Biotechnology 25 (1): 43–51.
Nuriliani, Ardaning, Ibnu Agus Ariyanto, Mei Santi, Andi Mahendra, Ni Wayan Erly Dewi, Arif Luthfi Nurul Huda, and Nastiti Wijayanti. 2013. “Aktivitas Sitotoksik Dan Apoptosis Ekstrak Spons Spesies A Anggota Ordo Astroporida Terhadap Sel HeLa (Cervical Cancer Cell Line).” Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati 18 (1): 53372.
Rahmawaty, R. G., M. H. Aziz, C. Dachwan, and E. Y. Sari. 2022. “Challenges for Legionella Pneumophila Detection in Indonesia.” Journal of Clinical. https://www.jcmid.id/index.php/JCMID/article/view/35.
Waters, Shelley, Mark Agostino, Silvia Lee, Ibnu Ariyanto, Nina Kresoje, Shay Leary, Kylie Munyard, et al. 2021. “Sequencing Directly from Clinical Specimens Reveals Genetic Variations in HCMV-Encoded Chemokine Receptor US28 That May Influence Antibody Levels and Interactions with Human Chemokines.” Microbiology Spectrum 9 (2): e0002021.
Waters, Shelley, Richard J. N. Allcock, Silvia Lee, Jonathan Downing, Ibnu Ariyanto, Shay Leary, Kylie Munyard, Ashley Irish, and Patricia Price. 2023. “Do Variations in the HLA-E Ligand Encoded by UL40 Distinguish Individuals Susceptible to HCMV Disease?” Human Immunology 84 (2): 75–79.
Waters, Shelley, Emily Brook, Silvia Lee, Riwanti Estiasari, Ibnu Ariyanto, and Patricia Price. 2018. “HIV Patients, Healthy Aging and Transplant Recipients Can Reveal the Hidden Footprints of CMV” 187 (February): 107–12.
Waters, Shelley, Silvia Lee, Ibnu Ariyanto, Nina Kresoje, Shay Leary, Kylie Munyard, Silvana Gaudieri, et al. 2022. “Sequencing of the Viral UL111a Gene Directly from Clinical Specimens Reveals Variants of HCMV-Encoded IL-10 That Are Associated with Altered Immune Responses to HCMV.” International Journal of Molecular Sciences 23 (9). https://doi.org/10.3390/ijms23094644.
Waters, Shelley, Silvia Lee, Ibnu Ariyanto, Shay Leary, Kylie Munyard, Silvana Gaudieri, Ashley Irish, Richard J. N. Allcock, and Patricia Price. 2022. “Variants of HCMV UL18 Sequenced Directly from Clinical Specimens Associate with Antibody and T-Cell Responses to HCMV.” International Journal of Molecular Sciences 23 (21). https://doi.org/10.3390/ijms232112911.
Wijaya, Ika Prasetya, Birry Karim, Mohamad Syahrir Azizi, Ibnu Ariyanto, Arif Mansjoer, Evy Yunihastuti, Kuntjoro Harimurti, Idrus Alwi, Silvia Lee, and Patricia Price. 2021. “Cytomegalovirus May Influence Vascular Endothelial Health in Indonesian HIV-Infected Patients after 5 Years on ART.” AIDS Research and Therapy 18 (1): 83.
Wulandari, Endah A. T., Ika Prasetya Wijaya, Birry Karim, Ibnu Ariyanto, Selita Agnes Tanudjaja, Silvia Lee, and Patricia Price. 2020. “Periodontitis and Cytomegalovirus Associate with Atherosclerosis among HIV Patients after 5 Years on ART.” Journal of Acquired Immune Deficiency Syndromes (1999) 85 (2): 195–200.